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Mechanisms of metabolic dysfunction in cancer-associated cachexia
Metabolic dysfunction contributes to the clinical deterioration observed in advanced cancer patients and is characterized by weight loss, skeletal muscle wasting, and atrophy of the adipose tissue. This systemic syndrome, termed cancer-associated cachexia (CAC), is a major cause of morbidity and mor...
Autores principales: | Petruzzelli, Michele, Wagner, Erwin F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782044/ https://www.ncbi.nlm.nih.gov/pubmed/26944676 http://dx.doi.org/10.1101/gad.276733.115 |
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