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AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes

Faithful execution of developmental programs relies on the acquisition of unique cell identities from pluripotent progenitors, a process governed by combinatorial inputs from numerous signaling cascades that ultimately dictate lineage-specific transcriptional outputs. Despite growing evidence that m...

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Detalles Bibliográficos
Autores principales: Young, Nathan P., Kamireddy, Anwesh, Van Nostrand, Jeanine L., Eichner, Lillian J., Shokhirev, Maxim Nikolaievich, Dayn, Yelena, Shaw, Reuben J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782048/
https://www.ncbi.nlm.nih.gov/pubmed/26944679
http://dx.doi.org/10.1101/gad.274142.115