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Long-term use of lithium and risk of colorectal adenocarcinoma: a nationwide case–control study
BACKGROUND: Lithium accumulates in the colon and inhibits the enzyme GSK-3β that possesses anti-carcinogenic effects. We therefore examined the association between lithium use and colorectal cancer risk in a nationwide study. METHODS: We used the Danish Cancer Registry to identify all patients diagn...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782204/ https://www.ncbi.nlm.nih.gov/pubmed/26867160 http://dx.doi.org/10.1038/bjc.2016.10 |