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Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve

Glioblastoma is a unique model of non-metastasising disease that kills the vast majority of patients through local growth, despite surgery and local irradiation. Glioblastoma cells are resistant to apoptotic stimuli, and their death occurs through autophagy. This review aims to critically present ou...

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Detalles Bibliográficos
Autores principales: Koukourakis, Michael I, Mitrakas, Achilleas G, Giatromanolaki, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782209/
https://www.ncbi.nlm.nih.gov/pubmed/26889975
http://dx.doi.org/10.1038/bjc.2016.19