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Performance characteristics between TDx®FLx and TBA™-25FR for the therapeutic drug monitoring of methotrexate

BACKGROUND: High-dose methotrexate (HDMTX) is used in the treatment of certain malignancies, including leptomeningeal metastases, systemic non-Hodgkin lymphoma, acute lymphoblastic leukemia, and osteosarcoma. High circulating levels of methotrexate can cause severe myelosuppression. The present stud...

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Detalles Bibliográficos
Autores principales: Kaneko, Tetsuya, Fujioka, Takashi, Suzuki, Yosuke, Sato, Yuhki, Itoh, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782285/
https://www.ncbi.nlm.nih.gov/pubmed/26958349
http://dx.doi.org/10.1186/s40780-016-0042-y