Anti-vascular effects of the cytosolic phospholipase A2 inhibitor AVX235 in a patient-derived basal-like breast cancer model

BACKGROUND: Group IVA cytosolic phospholipase A2 (cPLA2α) plays an important role in tumorigenesis and angiogenesis. It is overexpressed in basal-like breast cancer (BLBC), which is aggressive and usually triple-negative, making it unresponsive to current targeted therapies. Here, we evaluated the a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Eugene, Tunset, Hanna Maja, Cebulla, Jana, Vettukattil, Riyas, Helgesen, Heidi, Feuerherm, Astrid Jullumstrø, Engebråten, Olav, Mælandsmo, Gunhild Mari, Johansen, Berit, Moestue, Siver Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782288/
https://www.ncbi.nlm.nih.gov/pubmed/26951085
http://dx.doi.org/10.1186/s12885-016-2225-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782288/
https://www.ncbi.nlm.nih.gov/pubmed/26951085
http://dx.doi.org/10.1186/s12885-016-2225-1

Ejemplares similares