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Effect of calcitonin gene-related peptide antagonist on the cardiovascular events, mortality, and prostaglandin E(2) production by nitrate-induced tolerant rats with acute myocardial infarction

BACKGROUND: Anti-ischemic effects of NO releasing by nitroglycerin (NTG) and the release of calcitonin gene-related peptide (CGRP) are involved in the decrease of vascular remodeling in different cardiovascular diseases. Using a nitrate-free period is still generally required to prevent nitrate tole...

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Detalles Bibliográficos
Autores principales: Kezeli, Tamar, Rukhadze, Tamari, Gongadze, Nikoloz, Sukoyan, Galina, Dolidze, Nino, Chipashvili, Mariam, Mirziashvili, Makrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782301/
https://www.ncbi.nlm.nih.gov/pubmed/26958096
http://dx.doi.org/10.1186/s13167-016-0055-5