Single low dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission after artemether-lumefantrine in children with asymptomatic infection: a randomised, double-blind, placebo-controlled trial

BACKGROUND: A single low dose (0.25 mg/kg) of primaquine is recommended as a gametocytocide in combination with artemisinin-based combination therapies for Plasmodium falciparum but its effect on post-treatment gametocyte circulation and infectiousness to mosquitoes has not been quantified. METHODS:...

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Detalles Bibliográficos
Autores principales: Gonçalves, Bronner P., Tiono, Alfred B., Ouédraogo, Alphonse, Guelbéogo, Wamdaogo M., Bradley, John, Nebie, Issa, Siaka, Débé, Lanke, Kjerstin, Eziefula, Alice C., Diarra, Amidou, Pett, Helmi, Bougouma, Edith C., Sirima, Sodiomon B., Drakeley, Chris, Bousema, Teun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782330/
https://www.ncbi.nlm.nih.gov/pubmed/26952094
http://dx.doi.org/10.1186/s12916-016-0581-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782330/
https://www.ncbi.nlm.nih.gov/pubmed/26952094
http://dx.doi.org/10.1186/s12916-016-0581-y

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