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Cas3 is a limiting factor for CRISPR-Cas immunity in Escherichia coli cells lacking H-NS

BACKGROUND: CRISPR-Cas systems provide adaptive immunity to mobile genetic elements in prokaryotes. In many bacteria, including E. coli, a specialized ribonucleoprotein complex called Cascade enacts immunity by“ an interference reaction" between CRISPR encoded RNA (crRNA) and invader DNA sequen...

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Detalles Bibliográficos
Autores principales: Majsec, Kristina, Bolt, Edward L., Ivančić-Baće, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782391/
https://www.ncbi.nlm.nih.gov/pubmed/26956996
http://dx.doi.org/10.1186/s12866-016-0643-5