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Cas3 is a limiting factor for CRISPR-Cas immunity in Escherichia coli cells lacking H-NS
BACKGROUND: CRISPR-Cas systems provide adaptive immunity to mobile genetic elements in prokaryotes. In many bacteria, including E. coli, a specialized ribonucleoprotein complex called Cascade enacts immunity by“ an interference reaction" between CRISPR encoded RNA (crRNA) and invader DNA sequen...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782391/ https://www.ncbi.nlm.nih.gov/pubmed/26956996 http://dx.doi.org/10.1186/s12866-016-0643-5 |