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Bioinformatic analyses in early host response to Porcine Reproductive and Respiratory Syndrome virus (PRRSV) reveals pathway differences between pigs with alternate genotypes for a major host response QTL

BACKGROUND: A region on Sus scrofa chromosome 4 (SSC4) surrounding single nucleotide polymorphism (SNP) marker WUR10000125 (WUR) has been reported to be strongly associated with both weight gain and serum viremia in pigs after infection with PRRS virus (PRRSV). A proposed causal mutation in the guan...

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Detalles Bibliográficos
Autores principales: Schroyen, Martine, Eisley, Christopher, Koltes, James E., Fritz-Waters, Eric, Choi, Igseo, Plastow, Graham S., Guan, Leluo, Stothard, Paul, Bao, Hua, Kommadath, Arun, Reecy, James M., Lunney, Joan K., Rowland, Robert R. R., Dekkers, Jack C. M., Tuggle, Christopher K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782518/
https://www.ncbi.nlm.nih.gov/pubmed/26951612
http://dx.doi.org/10.1186/s12864-016-2547-z