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Next-generation genotyping of hypervariable loci in many individuals of a non-model species: technical and theoretical implications

BACKGROUND: Across species, diversity at the Major Histocompatibility Complex (MHC) is critical to disease resistance and population health; however, use of MHC diversity to quantify the genetic health of populations has been hampered by the extreme variation found in MHC genes. Next generation sequ...

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Detalles Bibliográficos
Autores principales: Grogan, Kathleen E., McGinnis, Gwendolyn J., Sauther, Michelle L., Cuozzo, Frank P., Drea, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782575/
https://www.ncbi.nlm.nih.gov/pubmed/26957424
http://dx.doi.org/10.1186/s12864-016-2503-y