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Next-generation genotyping of hypervariable loci in many individuals of a non-model species: technical and theoretical implications
BACKGROUND: Across species, diversity at the Major Histocompatibility Complex (MHC) is critical to disease resistance and population health; however, use of MHC diversity to quantify the genetic health of populations has been hampered by the extreme variation found in MHC genes. Next generation sequ...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782575/ https://www.ncbi.nlm.nih.gov/pubmed/26957424 http://dx.doi.org/10.1186/s12864-016-2503-y |