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9-Fluorenylmethyl (Fm) Disulfides: Biomimetic Precursors for Persulfides

[Image: see text] The development of a functional disulfide, FmSSPy-A (Fm = 9-fluorenylmethyl; Py = pyridinyl), is reported. It can effectively convert small molecule and protein thiols (−SH) to form −S-SFm adducts under mild conditions. This method allows for a H(2)S-free and biomimetic protocol to...

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Detalles Bibliográficos
Autores principales: Park, Chung-Min, Johnson, Brett A., Duan, Jicheng, Park, Jeong-Jin, Day, Jacob J., Gang, David, Qian, Wei-Jun, Xian, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782721/
https://www.ncbi.nlm.nih.gov/pubmed/26870874
http://dx.doi.org/10.1021/acs.orglett.5b03557