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Bioinformatics analysis identifies several intrinsically disordered human E3 ubiquitin-protein ligases
The ubiquitin-proteasome system targets misfolded proteins for degradation. Since the accumulation of such proteins is potentially harmful for the cell, their prompt removal is important. E3 ubiquitin-protein ligases mediate substrate ubiquitination by bringing together the substrate with an E2 ubiq...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
PeerJ Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782732/ https://www.ncbi.nlm.nih.gov/pubmed/26966660 http://dx.doi.org/10.7717/peerj.1725 |