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Potentiation of immunomodulatory antibody therapy with oncolytic viruses for treatment of cancer

Identification of the immune suppressive mechanisms active within the tumor microenvironment led to development of immunotherapeutic strategies aiming to reverse the immunosuppression and to enhance the function of tumor-infiltrating lymphocytes. Of those, cancer therapy with antibodies targeting th...

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Detalles Bibliográficos
Autores principales: Zamarin, Dmitriy, Wolchok, Jedd D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782939/
https://www.ncbi.nlm.nih.gov/pubmed/27119094
http://dx.doi.org/10.1038/mto.2014.4