Retargeted oncolytic adenovirus displaying a single variable domain of camelid heavy-chain-only antibody in a fiber protein

Conditionally replicative adenoviruses are promising agents for oncolytic virotherapy. Various approaches have been attempted to retarget adenoviruses to tumor-specific antigens to circumvent deficiency of receptor for adenoviral binding and to provide an additional level of tumor specificity. Funct...

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Detalles Bibliográficos
Autores principales: van Erp, Elisabeth A, Kaliberova, Lyudmila N, Kaliberov, Sergey A, Curiel, David T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782946/
https://www.ncbi.nlm.nih.gov/pubmed/27119101
http://dx.doi.org/10.1038/mto.2015.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782946/
https://www.ncbi.nlm.nih.gov/pubmed/27119101
http://dx.doi.org/10.1038/mto.2015.1

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