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Chimeric antigen receptor–engineered T cells as oncolytic virus carriers

The use of engineered T cells in adoptive transfer therapies has shown significant promise in treating hematological cancers. However, successes treating solid tumors are much less prevalent. Oncolytic viruses (OVs) have the capacity to induce specific lysis of tumor cells and indirectly impact tumo...

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Detalles Bibliográficos
Autores principales: VanSeggelen, Heather, Tantalo, Daniela GM, Afsahi, Arya, Hammill, Joanne A, Bramson, Jonathan L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782951/
https://www.ncbi.nlm.nih.gov/pubmed/27119109
http://dx.doi.org/10.1038/mto.2015.14