Combination of the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus as a new option for epi-virotherapeutic treatment of hepatocellular carcinoma

Epigenetic therapies such as histone deacetylase inhibitors (HDACi) not only have the capability to decrease tumor cell proliferation and to induce tumor cell death but also to silence antiviral response genes. Here, we investigated whether the combination of an oncolytic measles vaccine virus (MeV)...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruf, Benjamin, Berchtold, Susanne, Venturelli, Sascha, Burkard, Markus, Smirnow, Irina, Prenzel, Tanja, Henning, Stefan W, Lauer, Ulrich M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782956/
https://www.ncbi.nlm.nih.gov/pubmed/27119111
http://dx.doi.org/10.1038/mto.2015.19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782956/
https://www.ncbi.nlm.nih.gov/pubmed/27119111
http://dx.doi.org/10.1038/mto.2015.19

Ejemplares similares