Cargando…

Expression of anti-VEGF antibody together with anti-EGFR or anti-FAP enhances tumor regression as a result of vaccinia virotherapy

The tumor microenvironment plays an important role in tumor growth and progression. Here we demonstrate that vaccinia virus-mediated, constitutively expressed intratumoral antibodies against vascular endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR), and fibroblast activation...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Ting, Wang, Huiqiang, Chen, Nanhai G, Frentzen, Alexa, Minev, Boris, Szalay, Aladar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782963/
https://www.ncbi.nlm.nih.gov/pubmed/27119102
http://dx.doi.org/10.1038/mto.2015.3