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Expression of anti-VEGF antibody together with anti-EGFR or anti-FAP enhances tumor regression as a result of vaccinia virotherapy
The tumor microenvironment plays an important role in tumor growth and progression. Here we demonstrate that vaccinia virus-mediated, constitutively expressed intratumoral antibodies against vascular endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR), and fibroblast activation...
Autores principales: | Huang, Ting, Wang, Huiqiang, Chen, Nanhai G, Frentzen, Alexa, Minev, Boris, Szalay, Aladar A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782963/ https://www.ncbi.nlm.nih.gov/pubmed/27119102 http://dx.doi.org/10.1038/mto.2015.3 |
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