Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart

An orchestrated interplay of adaptor and signaling proteins at mechano-sensitive sites is essential to maintain cardiac contractility and when defective leads to heart failure. We recently showed that Integrin-linked Kinase (ILK), ß-Parvin and PINCH form the IPP-complex to grant tuned Protein Kinase...

Descripción completa

Detalles Bibliográficos
Autores principales: Hirth, Sofia, Bühler, Anja, Bührdel, John B., Rudeck, Steven, Dahme, Tillman, Rottbauer, Wolfgang, Just, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782988/
https://www.ncbi.nlm.nih.gov/pubmed/26954676
http://dx.doi.org/10.1371/journal.pone.0150323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782988/
https://www.ncbi.nlm.nih.gov/pubmed/26954676
http://dx.doi.org/10.1371/journal.pone.0150323

Ejemplares similares