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Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart

An orchestrated interplay of adaptor and signaling proteins at mechano-sensitive sites is essential to maintain cardiac contractility and when defective leads to heart failure. We recently showed that Integrin-linked Kinase (ILK), ß-Parvin and PINCH form the IPP-complex to grant tuned Protein Kinase...

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Detalles Bibliográficos
Autores principales:	Hirth, Sofia, Bühler, Anja, Bührdel, John B., Rudeck, Steven, Dahme, Tillman, Rottbauer, Wolfgang, Just, Steffen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782988/ https://www.ncbi.nlm.nih.gov/pubmed/26954676 http://dx.doi.org/10.1371/journal.pone.0150323

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