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Silencing Status Epilepticus-Induced BDNF Expression with Herpes Simplex Virus Type-1 Based Amplicon Vectors

Brain-derived neurotrophic factor (BDNF) has been found to produce pro- but also anti-epileptic effects. Thus, its validity as a therapeutic target must be verified using advanced tools designed to block or to enhance its signal. The aim of this study was to develop tools to silence the BDNF signal....

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Detalles Bibliográficos
Autores principales: Falcicchia, Chiara, Trempat, Pascal, Binaschi, Anna, Perrier-Biollay, Coline, Roncon, Paolo, Soukupova, Marie, Berthommé, Hervé, Simonato, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783051/
https://www.ncbi.nlm.nih.gov/pubmed/26954758
http://dx.doi.org/10.1371/journal.pone.0150995