Cargando…
Silencing Status Epilepticus-Induced BDNF Expression with Herpes Simplex Virus Type-1 Based Amplicon Vectors
Brain-derived neurotrophic factor (BDNF) has been found to produce pro- but also anti-epileptic effects. Thus, its validity as a therapeutic target must be verified using advanced tools designed to block or to enhance its signal. The aim of this study was to develop tools to silence the BDNF signal....
Autores principales: | Falcicchia, Chiara, Trempat, Pascal, Binaschi, Anna, Perrier-Biollay, Coline, Roncon, Paolo, Soukupova, Marie, Berthommé, Hervé, Simonato, Michele |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783051/ https://www.ncbi.nlm.nih.gov/pubmed/26954758 http://dx.doi.org/10.1371/journal.pone.0150995 |
Ejemplares similares
-
Improvement of HSV-1 based amplicon vectors for a safe and long-lasting gene therapy in non-replicating cells
por: Soukupová, Marie, et al.
Publicado: (2021) -
Multigene human artificial chromosome vector delivery with herpes simplex virus 1 amplicons
por: Chan, David YL, et al.
Publicado: (2020) -
MicroRNA profiles in hippocampal granule cells and plasma of rats with pilocarpine-induced epilepsy – comparison with human epileptic samples
por: Roncon, Paolo, et al.
Publicado: (2015) -
Herpes Virus Amplicon Vectors
por: de Silva, Suresh, et al.
Publicado: (2009) -
Enhanced Production of Herpes Simplex Virus 1 Amplicon Vectors by Gene Modification and Optimization of Packaging Cell Growth Medium
por: Fernández-Frías, Iván, et al.
Publicado: (2020)