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Decreased Laminin Expression by Human Lung Epithelial Cells and Fibroblasts Cultured in Acellular Lung Scaffolds from Aged Mice

The lung changes functionally and structurally with aging. However, age-related effects on the extracellular matrix (ECM) and corresponding effects on lung cell behavior are not well understood. We hypothesized that ECM from aged animals would induce aging-related phenotypic changes in healthy inocu...

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Detalles Bibliográficos
Autores principales: Godin, Lindsay M., Sandri, Brian J., Wagner, Darcy E., Meyer, Carolyn M., Price, Andrew P., Akinnola, Ifeolu, Weiss, Daniel J., Panoskaltsis-Mortari, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783067/
https://www.ncbi.nlm.nih.gov/pubmed/26954258
http://dx.doi.org/10.1371/journal.pone.0150966