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Decreased Laminin Expression by Human Lung Epithelial Cells and Fibroblasts Cultured in Acellular Lung Scaffolds from Aged Mice
The lung changes functionally and structurally with aging. However, age-related effects on the extracellular matrix (ECM) and corresponding effects on lung cell behavior are not well understood. We hypothesized that ECM from aged animals would induce aging-related phenotypic changes in healthy inocu...
Autores principales: | Godin, Lindsay M., Sandri, Brian J., Wagner, Darcy E., Meyer, Carolyn M., Price, Andrew P., Akinnola, Ifeolu, Weiss, Daniel J., Panoskaltsis-Mortari, Angela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783067/ https://www.ncbi.nlm.nih.gov/pubmed/26954258 http://dx.doi.org/10.1371/journal.pone.0150966 |
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