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Cyclin-Dependent Kinase CRK9, Required for Spliced Leader trans Splicing of Pre-mRNA in Trypanosomes, Functions in a Complex with a New L-Type Cyclin and a Kinetoplastid-Specific Protein

In eukaryotes, cyclin-dependent kinases (CDKs) control the cell cycle and critical steps in gene expression. The lethal parasite Trypanosoma brucei, member of the phylogenetic order Kinetoplastida, possesses eleven CDKs which, due to high sequence divergence, were generically termed CDC2-related kin...

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Detalles Bibliográficos
Autores principales: Badjatia, Nitika, Park, Sung Hee, Ambrósio, Daniela L., Kirkham, Justin K., Günzl, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783070/
https://www.ncbi.nlm.nih.gov/pubmed/26954683
http://dx.doi.org/10.1371/journal.ppat.1005498