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The Mechanism of Mycobacterium smegmatis PafA Self-Pupylation

PafA, the prokaryotic ubiquitin-like protein (Pup) ligase, catalyzes the Pup modification of bacterial proteins and targets the substrates for proteasomal degradation. It has been reported that that M. smegmatis PafA can be poly-pupylated. In this study, the mechanism of PafA self-pupylation is expl...

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Detalles Bibliográficos
Autores principales: Chen, Xuejie, Li, Chandan, Wang, Li, Liu, Yi, Li, Chuanyou, Zhang, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783102/
https://www.ncbi.nlm.nih.gov/pubmed/26953889
http://dx.doi.org/10.1371/journal.pone.0151021