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Rapid HIV-1 Disease Progression in Individuals Infected with a Virus Adapted to Its Host Population

HIV-1 escape from CTL is predictable based on the Human Leukocyte Antigen (HLA) class I alleles expressed by the host. As such, HIV-1 sequences circulating in a population of hosts will harbor escape mutations specific to the HLA alleles of that population. In theory, this should increase the freque...

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Detalles Bibliográficos
Autores principales: Katoh, Jiro, Kawana-Tachikawa, Ai, Shimizu, Akihisa, Zhu, Dayong, Han, Chungyong, Nakamura, Hitomi, Koga, Michiko, Kikuchi, Tadashi, Adachi, Eisuke, Koibuchi, Tomohiko, Gao, George F., Brumme, Zabrina L., Iwamoto, Aikichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783116/
https://www.ncbi.nlm.nih.gov/pubmed/26953793
http://dx.doi.org/10.1371/journal.pone.0150397