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Rapid HIV-1 Disease Progression in Individuals Infected with a Virus Adapted to Its Host Population
HIV-1 escape from CTL is predictable based on the Human Leukocyte Antigen (HLA) class I alleles expressed by the host. As such, HIV-1 sequences circulating in a population of hosts will harbor escape mutations specific to the HLA alleles of that population. In theory, this should increase the freque...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783116/ https://www.ncbi.nlm.nih.gov/pubmed/26953793 http://dx.doi.org/10.1371/journal.pone.0150397 |