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Mapping DNA methylation across development, genotype, and schizophrenia in the human frontal cortex

DNA methylation (DNAm) is important in brain development, and potentially in schizophrenia. We characterized DNAm in prefrontal cortex from 335 non-psychiatric controls across the lifespan and 191 patients with schizophrenia, and identified widespread changes in the transition from prenatal to postn...

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Detalles Bibliográficos
Autores principales: Jaffe, Andrew E., Gao, Yuan, Deep-Soboslay, Amy, Tao, Ran, Hyde, Thomas M., Weinberger, Daniel R., Kleinman, Joel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783176/
https://www.ncbi.nlm.nih.gov/pubmed/26619358
http://dx.doi.org/10.1038/nn.4181