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Mapping DNA methylation across development, genotype, and schizophrenia in the human frontal cortex
DNA methylation (DNAm) is important in brain development, and potentially in schizophrenia. We characterized DNAm in prefrontal cortex from 335 non-psychiatric controls across the lifespan and 191 patients with schizophrenia, and identified widespread changes in the transition from prenatal to postn...
Autores principales: | Jaffe, Andrew E., Gao, Yuan, Deep-Soboslay, Amy, Tao, Ran, Hyde, Thomas M., Weinberger, Daniel R., Kleinman, Joel E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783176/ https://www.ncbi.nlm.nih.gov/pubmed/26619358 http://dx.doi.org/10.1038/nn.4181 |
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