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Spontaneous cleavage of proteins at serine and threonine is facilitated by zinc

Old proteins are widely distributed in the body. Over time, they deteriorate and many spontaneous reactions, for example isomerisation of Asp and Asn, can be replicated by incubation of peptides under physiological conditions. One of the signatures of long‐lived proteins that has proven to be diffic...

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Detalles Bibliográficos
Autores principales: Lyons, Brian, Kwan, Ann H., Truscott, Roger J.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783340/
https://www.ncbi.nlm.nih.gov/pubmed/26751411
http://dx.doi.org/10.1111/acel.12428