Defects in MAP1S‐mediated autophagy cause reduction in mouse lifespans especially when fibronectin is overexpressed

Autophagy is a cellular process that executes the turnover of dysfunctional organelles and misfolded or abnormally aggregated proteins. Microtubule‐associated protein MAP1S interacts with autophagy marker LC3 and positively regulates autophagy flux. LC3 binds with fibronectin mRNA and facilitates it...

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Detalles Bibliográficos
Autores principales: Li, Wenjiao, Zou, Jing, Yue, Fei, Song, Kun, Chen, Qi, McKeehan, Wallace L., Wang, Fen, Xu, Guibin, Huang, Hai, Yi, Jinglin, Liu, Leyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783353/
https://www.ncbi.nlm.nih.gov/pubmed/26750654
http://dx.doi.org/10.1111/acel.12441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783353/
https://www.ncbi.nlm.nih.gov/pubmed/26750654
http://dx.doi.org/10.1111/acel.12441

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