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Methylene blue alleviates nuclear and mitochondrial abnormalities in progeria

Hutchinson–Gilford progeria syndrome (HGPS), a fatal premature aging disease, is caused by a single‐nucleotide mutation in the LMNA gene. Previous reports have focused on nuclear phenotypes in HGPS cells, yet the potential contribution of the mitochondria, a key player in normal aging, remains uncle...

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Detalles Bibliográficos
Autores principales: Xiong, Zheng‐Mei, Choi, Ji Young, Wang, Kun, Zhang, Haoyue, Tariq, Zeshan, Wu, Di, Ko, Eunae, LaDana, Christina, Sesaki, Hiromi, Cao, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783354/
https://www.ncbi.nlm.nih.gov/pubmed/26663466
http://dx.doi.org/10.1111/acel.12434