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Methylene blue alleviates nuclear and mitochondrial abnormalities in progeria
Hutchinson–Gilford progeria syndrome (HGPS), a fatal premature aging disease, is caused by a single‐nucleotide mutation in the LMNA gene. Previous reports have focused on nuclear phenotypes in HGPS cells, yet the potential contribution of the mitochondria, a key player in normal aging, remains uncle...
Autores principales: | Xiong, Zheng‐Mei, Choi, Ji Young, Wang, Kun, Zhang, Haoyue, Tariq, Zeshan, Wu, Di, Ko, Eunae, LaDana, Christina, Sesaki, Hiromi, Cao, Kan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783354/ https://www.ncbi.nlm.nih.gov/pubmed/26663466 http://dx.doi.org/10.1111/acel.12434 |
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