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The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells

Multiple sclerosis (MS) is an inflammatory, demyelinating disorder of the central nervous system that develops in genetically susceptible individuals. The majority of the MS-associated gene variants are located in genetic regions with importance for T-cell differentiation. Vitamin D is a potent immu...

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Detalles Bibliográficos
Autores principales: Berge, T, Leikfoss, I S, Brorson, I S, Bos, S D, Page, C M, Gustavsen, M W, Bjølgerud, A, Holmøy, T, Celius, E G, Damoiseaux, J, Smolders, J, Harbo, H F, Spurkland, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783434/
https://www.ncbi.nlm.nih.gov/pubmed/26765264
http://dx.doi.org/10.1038/gene.2015.61