The RNA-binding protein Mex3B is a coreceptor of Toll-like receptor 3 in innate antiviral response

Recognition of viral dsRNA by Toll-like receptor 3 (TLR3) leads to induction of interferons (IFNs) and proinflammatory cytokines, and innate antiviral response. Here we identified the RNA-binding protein Mex3B as a positive regulator of TLR3-mediated signaling by expression cloning screens. Cells fr...

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Detalles Bibliográficos
Autores principales: Yang, Yan, Wang, Su-Yun, Huang, Zhe-Fu, Zou, Hong-Mei, Yan, Bing-Ru, Luo, Wei-Wei, Wang, Yan-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783467/
https://www.ncbi.nlm.nih.gov/pubmed/26823206
http://dx.doi.org/10.1038/cr.2016.16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783467/
https://www.ncbi.nlm.nih.gov/pubmed/26823206
http://dx.doi.org/10.1038/cr.2016.16

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