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Bacitracin Inhibits the Migration of U87-MG Glioma Cells via Interferences of the Integrin Outside-in Signaling Pathway

OBJECTIVE: Protein disulfide isomerase (PDI) acts as a chaperone on the cell surface, and it has been reported that PDI is associated with the tumor cell migration and invasion. The aims of this study are to investigate the anti-migration effect of bacitracin, which is an inhibitor of PDI, and the a...

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Detalles Bibliográficos
Autores principales: Li, Songyuan, Li, Chunhao, Ryu, Hyang-Hwa, Lim, Sa-Hoe, Jang, Woo-Youl, Jung, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Neurosurgical Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783475/
https://www.ncbi.nlm.nih.gov/pubmed/26962415
http://dx.doi.org/10.3340/jkns.2016.59.2.106