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TSLP production by dendritic cells is modulated by IL‐1β and components of the endoplasmic reticulum stress response

Thymic stromal lymphopoietin (TSLP) produced by epithelial cells acts on dendritic cells (DCs) to drive differentiation of T(H)2‐cells, and is therefore important in allergic disease pathogenesis. However, DCs themselves make significant amounts of TSLP in response to microbial products, but little...

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Detalles Bibliográficos
Autores principales: Elder, Matthew J., Webster, Steven J., Williams, David L., Gaston, J. S. Hill, Goodall, Jane C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783504/
https://www.ncbi.nlm.nih.gov/pubmed/26573878
http://dx.doi.org/10.1002/eji.201545537