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Dual Role of ROS as Signal and Stress Agents: Iron Tips the Balance in favor of Toxic Effects

Iron is essential for life, while also being potentially harmful. Therefore, its level is strictly monitored and complex pathways have evolved to keep iron safely bound to transport or storage proteins, thereby maintaining homeostasis at the cellular and systemic levels. These sequestration mechanis...

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Detalles Bibliográficos
Autores principales: Gammella, Elena, Recalcati, Stefania, Cairo, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783558/
https://www.ncbi.nlm.nih.gov/pubmed/27006749
http://dx.doi.org/10.1155/2016/8629024