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BALB/c-congenic ANP32B-deficient mice reveal a modifying locus that determines viability

We previously found that deletion of the multifunctional factor ANP32B (a.k.a. SSP29, APRIL, PAL31, PHAPI2) resulted in a severe but strain-specific defect resulting in perinatal lethality. The difficulty in generating an adult cohort of ANP32B-deficient animals limited our ability to examine adult...

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Detalles Bibliográficos
Autores principales: Leo, Vonny I., Bunte, Ralph M., Reilly, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783651/
https://www.ncbi.nlm.nih.gov/pubmed/26558540
http://dx.doi.org/10.1538/expanim.15-0062