Inter-molecular β-sheet structure facilitates lung-targeting siRNA delivery

Size-dependent passive targeting based on the characteristics of tissues is a basic mechanism of drug delivery. While the nanometer-sized particles are efficiently captured by the liver and spleen, the micron-sized particles are most likely entrapped within the lung owing to its unique capillary str...

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Detalles Bibliográficos
Autores principales: Zhou, Jihan, Li, Dong, Wen, Hao, Zheng, Shuquan, Su, Cuicui, Yi, Fan, Wang, Jue, Liang, Zicai, Tang, Tao, Zhou, Demin, Zhang, Li-He, Liang, Dehai, Du, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783658/
https://www.ncbi.nlm.nih.gov/pubmed/26955887
http://dx.doi.org/10.1038/srep22731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783658/
https://www.ncbi.nlm.nih.gov/pubmed/26955887
http://dx.doi.org/10.1038/srep22731

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