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In vivo reprogramming reactive glia into iPSCs to produce new neurons in the cortex following traumatic brain injury

Traumatic brain injury (TBI) results in a significant amount of cell death in the brain. Unfortunately, the adult mammalian brain possesses little regenerative potential following injury and little can be done to reverse the initial brain damage caused by trauma. Reprogramming adult cells to generat...

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Detalles Bibliográficos
Autores principales: Gao, Xiang, Wang, Xiaoting, Xiong, Wenhui, Chen, Jinhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783661/
https://www.ncbi.nlm.nih.gov/pubmed/26957147
http://dx.doi.org/10.1038/srep22490