Sepsis-induced elevation in plasma serotonin facilitates endothelial hyperpermeability

Hyperpermeability of the endothelial barrier and resulting microvascular leakage are a hallmark of sepsis. Our studies describe the mechanism by which serotonin (5-HT) regulates the microvascular permeability during sepsis. The plasma 5-HT levels are significantly elevated in mice made septic by cec...

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Detalles Bibliográficos
Autores principales: Li, Yicong, Hadden, Coedy, Cooper, Anthonya, Ahmed, Asli, Wu, Hong, Lupashin, Vladimir V., Mayeux, Philip R., Kilic, Fusun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783700/
https://www.ncbi.nlm.nih.gov/pubmed/26956613
http://dx.doi.org/10.1038/srep22747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783700/
https://www.ncbi.nlm.nih.gov/pubmed/26956613
http://dx.doi.org/10.1038/srep22747

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