T-cell libraries allow simple parallel generation of multiple peptide-specific human T-cell clones

Isolation of peptide-specific T-cell clones is highly desirable for determining the role of T-cells in human disease, as well as for the development of therapies and diagnostics. However, generation of monoclonal T-cells with the required specificity is challenging and time-consuming. Here we descri...

Descripción completa

Detalles Bibliográficos
Autores principales: Theaker, Sarah M., Rius, Cristina, Greenshields-Watson, Alexander, Lloyd, Angharad, Trimby, Andrew, Fuller, Anna, Miles, John J., Cole, David K., Peakman, Mark, Sewell, Andrew K., Dolton, Garry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783706/
https://www.ncbi.nlm.nih.gov/pubmed/26826277
http://dx.doi.org/10.1016/j.jim.2016.01.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783706/
https://www.ncbi.nlm.nih.gov/pubmed/26826277
http://dx.doi.org/10.1016/j.jim.2016.01.014

Ejemplares similares