E-selectin-targeting delivery of microRNAs by microparticles ameliorates endothelial inflammation and atherosclerosis

E-selectin is a surface marker of endothelial cell (EC) inflammation, one of the hallmarks of atherogenesis. Thus, we tested the hypothesis that delivery of microRNA (miR)-146a and miR-181b with an E-selectin-targeting multistage vector (ESTA-MSV) to inflamed endothelium covering atherosclerotic pla...

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Detalles Bibliográficos
Autores principales: Ma, Shuangtao, Tian, Xiao Yu, Zhang, Yunrong, Mu, Chaofeng, Shen, Haifa, Bismuth, Jean, Pownall, Henry J., Huang, Yu, Wong, Wing Tak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783714/
https://www.ncbi.nlm.nih.gov/pubmed/26956647
http://dx.doi.org/10.1038/srep22910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783714/
https://www.ncbi.nlm.nih.gov/pubmed/26956647
http://dx.doi.org/10.1038/srep22910

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