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E-selectin-targeting delivery of microRNAs by microparticles ameliorates endothelial inflammation and atherosclerosis
E-selectin is a surface marker of endothelial cell (EC) inflammation, one of the hallmarks of atherogenesis. Thus, we tested the hypothesis that delivery of microRNA (miR)-146a and miR-181b with an E-selectin-targeting multistage vector (ESTA-MSV) to inflamed endothelium covering atherosclerotic pla...
Autores principales: | Ma, Shuangtao, Tian, Xiao Yu, Zhang, Yunrong, Mu, Chaofeng, Shen, Haifa, Bismuth, Jean, Pownall, Henry J., Huang, Yu, Wong, Wing Tak |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783714/ https://www.ncbi.nlm.nih.gov/pubmed/26956647 http://dx.doi.org/10.1038/srep22910 |
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