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PEGylated substrates of NSP4 protease: A tool to study protease specificity

Herein we present the synthesis of a novel type of peptidomimetics composed of repeating diaminopropionic acid residues modified with structurally diverse heterobifunctional polyethylene glycol chains (abbreviated as DAPEG). Based on the developed compounds, a library of fluorogenic substrates was s...

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Detalles Bibliográficos
Autores principales: Wysocka, Magdalena, Gruba, Natalia, Grzywa, Renata, Giełdoń, Artur, Bąchor, Remigiusz, Brzozowski, Krzysztof, Sieńczyk, Marcin, Dieter, Jenne, Szewczuk, Zbigniew, Rolka, Krzysztof, Lesner, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783772/
https://www.ncbi.nlm.nih.gov/pubmed/26955973
http://dx.doi.org/10.1038/srep22856