Biological Evaluation of Double Point Modified Analogues of 1,25-Dihydroxyvitamin D(2) as Potential Anti-Leukemic Agents

Structurally similar double-point modified analogues of 1,25-dihydroxyvitamin D(2) (1,25D(2)) were screened in vitro for their pro-differentiating activity against the promyeloid cell line HL60. Their affinities towards human full length vitamin D receptor (VDR) and metabolic stability against human...

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Detalles Bibliográficos
Autores principales: Corcoran, Aoife, Nadkarni, Sharmin, Yasuda, Kaori, Sakaki, Toshiyuki, Brown, Geoffrey, Kutner, Andrzej, Marcinkowska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783874/
https://www.ncbi.nlm.nih.gov/pubmed/26840307
http://dx.doi.org/10.3390/ijms17020091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783874/
https://www.ncbi.nlm.nih.gov/pubmed/26840307
http://dx.doi.org/10.3390/ijms17020091

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