Metformin Prevents Renal Fibrosis in Mice with Unilateral Ureteral Obstruction and Inhibits Ang II-Induced ECM Production in Renal Fibroblasts

Renal fibrosis is the final common pathway of chronic kidney disease (CKD), and no effective medication is available clinically for managing its progression. Metformin was initially developed as an anti-diabetic drug and recently gained attention for its potential in the treatment of other diseases....

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Detalles Bibliográficos
Autores principales: Shen, Yang, Miao, Naijun, Xu, Jinlan, Gan, Xinxin, Xu, Dan, Zhou, Li, Xue, Hong, Zhang, Wei, Lu, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783880/
https://www.ncbi.nlm.nih.gov/pubmed/26805826
http://dx.doi.org/10.3390/ijms17020146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783880/
https://www.ncbi.nlm.nih.gov/pubmed/26805826
http://dx.doi.org/10.3390/ijms17020146

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